| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsinogen B |
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| Ligand | BDBM50126829 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_49607 (CHEMBL661258) |
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| IC50 | 25000±n/a nM |
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| Citation |  McGovern, SL; Shoichet, BK Kinase inhibitors: not just for kinases anymore. J Med Chem46:1478-83 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsinogen B |
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| Name: | Chymotrypsinogen B |
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| Synonyms: | A0A2R8YG87_HUMAN | Beta-chymotrypsin | CTRB1 | Chymotrypsin B chain A | Chymotrypsin B chain B | Chymotrypsin B chain C | Chymotrypsinogen B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27871.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_216634 |
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| Residue: | 263 |
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| Sequence: | MAFLWLLSCWALLGTTFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFC
GGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNND
ITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPL
LSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCST
SSPGVYARVTKLIPWVQKILAAN
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| BDBM50126829 |
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| n/a |
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| Name | BDBM50126829 |
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| Synonyms: | (E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl)-3-phenylprop-2-en-1-one | 1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl)-3-phenylprop-2-en-1-one | 1-[6-(3-Acetyl-2,4,6-trihydroxy-5-methyl-benzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl]-3-phenyl-propenone | CHEMBL34241 | R5648 (Rottlerin) | ROTTLERIN |
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| Type | Small organic molecule |
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| Emp. Form. | C30H28O8 |
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| Mol. Mass. | 516.5385 |
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| SMILES | CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c3C=CC(C)(C)Oc3c(C(=O)C=Cc3ccccc3)c2O)c1O |w:26.26,c:16| |
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| Structure | 
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