| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine receptor (H3) |
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| Ligand | BDBM50126886 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_83651 |
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| Ki | 66±n/a nM |
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| Citation |  Mikó T; Ligneau X; Pertz HH; Ganellin CR; Arrang JM; Schwartz JC; Schunack W; Stark H Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds. J Med Chem 46:1523-30 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine receptor (H3) |
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| Name: | Histamine receptor (H3 and H4) |
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| Synonyms: | G-protein coupled receptor 97 | HH3R | HISTAMINE H3 | HRH3 | Histamine H3 Receptor | Histamine H3 receptor (H3) | Histamine H3L | Histamine receptor (H3 and H4) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48691.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Binding assays were using CHO cells stably expressing hH3R receptors. |
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| Residue: | 445 |
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| Sequence: | MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
RAFTKLLCPQKLKIQPHSSLEHCWK
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| BDBM50126886 |
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| n/a |
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| Name | BDBM50126886 |
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| Synonyms: | CHEMBL284528 | Cyclopropyl-[4-(4-piperidin-1-ylmethyl-benzyloxy)-phenyl]-methanone; compound with oxalic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27NO2 |
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| Mol. Mass. | 349.466 |
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| SMILES | O=C(C1CC1)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1 |
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| Structure | 
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