| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H3 receptor |
|---|
| Ligand | BDBM50126903 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_83651 (CHEMBL693111) |
|---|
| Ki | 42±n/a nM |
|---|
| Citation |  Mikó, T; Ligneau, X; Pertz, HH; Ganellin, CR; Arrang, JM; Schwartz, JC; Schunack, W; Stark, H Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds. J Med Chem46:1523-30 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H3 receptor |
|---|
| Name: | Histamine H3 receptor |
|---|
| Synonyms: | G-protein coupled receptor 97 | GPCR97 | HH3R | HISTAMINE H3 | HRH3 | HRH3_HUMAN | Histamine H3 receptor (H3) | Histamine H3L | Histamine receptor (H3 and H4) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 48691.47 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Binding assays were using CHO cells stably expressing hH3R receptors. |
|---|
| Residue: | 445 |
|---|
| Sequence: | MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
SAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAA
GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSV
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
RAFTKLLCPQKLKIQPHSSLEHCWK
|
|
|
|---|
| BDBM50126903 |
|---|
| n/a |
|---|
| Name | BDBM50126903 |
|---|
| Synonyms: | 1-[4-(4-Chloro-3-methyl-phenoxymethyl)-benzyl]-piperidine; compound with oxalic acid | CHEMBL36630 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H24ClNO |
|---|
| Mol. Mass. | 329.864 |
|---|
| SMILES | Cc1cc(OCc2ccc(CN3CCCCC3)cc2)ccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
