| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM50126895 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_85342 (CHEMBL695016) |
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| Kd | 14125.38±n/a nM |
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| Citation |  Mikó, T; Ligneau, X; Pertz, HH; Ganellin, CR; Arrang, JM; Schwartz, JC; Schunack, W; Stark, H Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds. J Med Chem46:1523-30 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_CAVPO | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40567.22 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | For the H2 receptor-binding assays, guinea pig striatum was used. |
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| Residue: | 359 |
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| Sequence: | MAFNGTVPSFCMDFTVYKVTISVILIILILVTVAGNVVVCLAVGLNRRLRSLTNCFIVSL
AVTDLLLGLLVLPFSAIYQLSCKWSFSKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLITPARVAISLVFIWVISITLSFLSIHLGWNSRNETSKDNDTIVKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYFRIFKIAREQARRINHIGSWKAATIREHKATVTLAAVM
GAFIICWFPYFTVFVYRGLKGDDAVNEVFEDVVLWLGYANSALNPILYAALNRDFRTAYH
QLFCCRLASHNSHETSLRLNNSQLNRSQCQEPRWQEDKPLNLQVWSGTEVTAPQGATNR
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| BDBM50126895 |
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| n/a |
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| Name | BDBM50126895 |
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| Synonyms: | 1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-ethanone oxime | CHEMBL39716 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N2O2 |
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| Mol. Mass. | 338.4433 |
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| SMILES | CC(N=O)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1 |
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| Structure | 
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