| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM50126875 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_83477 (CHEMBL693948) |
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| Kd | 30.9±n/a nM |
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| Citation |  Mikó, T; Ligneau, X; Pertz, HH; Ganellin, CR; Arrang, JM; Schwartz, JC; Schunack, W; Stark, H Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds. J Med Chem46:1523-30 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48753.61 |
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| Organism: | GUINEA PIG |
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| Description: | HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35 |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAF
VADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCT
SSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSG
GSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGARE
AGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHSSLEHCWK
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| BDBM50126875 |
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| n/a |
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| Name | BDBM50126875 |
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| Synonyms: | CHEMBL39951 | Cyclopentyl-[4-(4-piperidin-1-ylmethyl-benzyloxy)-phenyl]-methanone; compound with oxalic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C25H31NO2 |
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| Mol. Mass. | 377.5191 |
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| SMILES | O=C(C1CCCC1)c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1 |
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| Structure | 
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