| Reaction Details |
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 | Report a problem with these data |
| Target | 6-phosphogluconate dehydrogenase, decarboxylating |
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| Ligand | BDBM50148770 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_4339 (CHEMBL619158) |
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| Ki | 784000±n/a nM |
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| Citation |  Dardonville, C; Rinaldi, E; Barrett, MP; Brun, R; Gilbert, IH; Hanau, S Selective inhibition of Trypanosoma brucei 6-phosphogluconate dehydrogenase by high-energy intermediate and transition-state analogues. J Med Chem47:3427-37 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| 6-phosphogluconate dehydrogenase, decarboxylating |
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| Name: | 6-phosphogluconate dehydrogenase, decarboxylating |
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| Synonyms: | 6-phosphogluconate dehydrogenase | 6-phosphogluconate dehydrogenase (6PGD) | 6PGD_HUMAN | PGD | PGDH |
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| Type: | Protein |
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| Mol. Mass.: | 53143.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P52209 |
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| Residue: | 483 |
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| Sequence: | MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE
MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG
ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG
HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL
KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA
SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL
MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM
PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS
YNA
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| BDBM50148770 |
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| n/a |
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| Name | BDBM50148770 |
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| Synonyms: | ((R)-2-Hydroxy-3-phosphonooxy-propane-1-sulfinyl)-acetic acid | CHEMBL117133 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H11O8PS |
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| Mol. Mass. | 262.175 |
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| SMILES | O[C@H](COP(O)(O)=O)CS(=O)CC(O)=O |
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| Structure | 
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