| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocortin receptor 5 |
|---|
| Ligand | BDBM50141026 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106669 (CHEMBL714653) |
|---|
| EC50 | 0.120000±n/a nM |
|---|
| Citation |  Han, G; Haskell-Luevano, C; Kendall, L; Bonner, G; Hadley, ME; Cone, RD; Hruby, VJ De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach. J Med Chem47:1514-26 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocortin receptor 5 |
|---|
| Name: | Melanocortin receptor 5 |
|---|
| Synonyms: | MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36966.58 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P41149 |
|---|
| Residue: | 325 |
|---|
| Sequence: | MNSSSTLTVLNLTLNASEDGILGSNVKNKSLACEEMGIAVEVFLTLGLVSLLENILVIGA
IVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDS
MICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIY
YESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRTSMKGAITL
TMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQ
EMRRTFKEIVCCHGFRRPCRLLGGY
|
|
|
|---|
| BDBM50141026 |
|---|
| n/a |
|---|
| Name | BDBM50141026 |
|---|
| Synonyms: | 1N-(1-carbamoyl-2-hydroxypropyl)-15-[3-amino(imino)methylaminopropyl]-6-(1-amino-2-phenylethylcarboxamido)-12-benzyl-9-(1H-5-imidazolylmethyl)-18-(1H-3-indolylmethyl)-7,10,13,16,19-pentaoxo-3,4-dithia-8,11,14,17,20-pentaazacycloicosane-1-carboxam | CHEMBL410404 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C51H65N15O9S2 |
|---|
| Mol. Mass. | 1096.287 |
|---|
| SMILES | C[C@@H](O)[C@H](NC(=O)[C@H]1CSSC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N1)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
