Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50369584 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_79980 (CHEMBL690417) |
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Ki | 0.3±n/a nM |
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Citation | Reid, RC; Pattenden, LK; Tyndall, JD; Martin, JL; Walsh, T; Fairlie, DP Countering cooperative effects in protease inhibitors using constrained beta-strand-mimicking templates in focused combinatorial libraries. J Med Chem47:1641-51 (2004) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50369584 |
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n/a |
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Name | BDBM50369584 |
Synonyms: | CHEMBL1790230 |
Type | Small organic molecule |
Emp. Form. | C43H54N6O6 |
Mol. Mass. | 750.9255 |
SMILES | CC[C@@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(OCCCNC1=O)cc2)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)c1ccc2ccccc2n1)C(C)C |
Structure |
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