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TargetGag-Pol polyprotein [489-587]
LigandBDBM50369584
Substrate/Competitorn/a
Meas. Tech.ChEMBL_79980 (CHEMBL690417)
Ki 0.3±n/a nM
Citation Reid, RCPattenden, LKTyndall, JDMartin, JLWalsh, TFairlie, DP Countering cooperative effects in protease inhibitors using constrained beta-strand-mimicking templates in focused combinatorial libraries. J Med Chem47:1641-51 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50369584
n/a
NameBDBM50369584
Synonyms:CHEMBL1790230
TypeSmall organic molecule
Emp. Form.C43H54N6O6
Mol. Mass.750.9255
SMILESCC[C@@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(OCCCNC1=O)cc2)NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)c1ccc2ccccc2n1)C(C)C
Structure
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