| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50143604 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_145190 (CHEMBL754435) |
|---|
| Ki | 940±n/a nM |
|---|
| Citation |  Zhang, A; Xiong, W; Hilbert, JE; DeVita, EK; Bidlack, JM; Neumeyer, JL 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols. J Med Chem47:1886-8 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 40382.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
|---|
| Residue: | 372 |
|---|
| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50143604 |
|---|
| n/a |
|---|
| Name | BDBM50143604 |
|---|
| Synonyms: | 13-cyclopropylmethyl-1,16-dimethyl-(1R,12R,16R)-7-thia-5,13-diazatetracyclo[10.3.1.02,10.04,8]hexadeca-2(10),3,5,8-tetraen-6-amine | CHEMBL56356 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H25N3S |
|---|
| Mol. Mass. | 327.487 |
|---|
| SMILES | C[C@H]1[C@H]2Cc3cc4sc(N)nc4cc3[C@]1(C)CCN2CC1CC1 |TLB:19:18:1:13.4.3| |
|---|
| Structure | 
|
|---|
Search and Browse
