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TargetPTGFR
LigandBDBM50035622
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302844
Ki 129±n/a nM
Citation Selliah RDHellberg MRSharif NAMcLaughlin MAWilliams GWScott DAEarnest DHaggard KSDean WDDelgado PGaines MSConrow REKlimko PG AL-12182, a novel 11-oxa prostaglandin analog with topical ocular hypotensive activity in the monkey. Bioorg Med Chem Lett 14:4525-8 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
PTGFR
Name:Prostanoid FP receptor
Synonyms:PGF receptor | PGF2 alpha receptor | ProstaglandinF2Alpha
Type:Enzyme Catalytic Domain
Mol. Mass.:41044.75
Organism:BOVINE
Description:ProstaglandinF2Alpha PTGFR BOVINE::P37289
Residue:362
Sequence:
MSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQ
KYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGL
CPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQ
ASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQG
RSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILD
PWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQT
ST
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50035622
n/a
NameBDBM50035622
Synonyms:(5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dien-1-oic acid | CHEMBL815 | DINOPROST | PGF2alpha | l-PGF2-alpha | l-Prostaglandin F2-alpha | prostaglandin F2alpha
TypeSmall organic molecule
Emp. Form.C20H34O5
Mol. Mass.354.481
SMILESCCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r|
Structure
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