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TargetProstaglandin F2-alpha receptor
LigandBDBM50150895
Substrate/Competitorn/a
Meas. Tech.ChEMBL_310565
EC50>10000±n/a nM
Citation Selliah RDHellberg MRSharif NAMcLaughlin MAWilliams GWScott DAEarnest DHaggard KSDean WDDelgado PGaines MSConrow REKlimko PG AL-12182, a novel 11-oxa prostaglandin analog with topical ocular hypotensive activity in the monkey. Bioorg Med Chem Lett 14:4525-8 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin F2-alpha receptor
Name:Prostaglandin F2-alpha receptor
Synonyms:PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor
Type:Enzyme
Mol. Mass.:40072.29
Organism:Homo sapiens (Human)
Description:P43088
Residue:359
Sequence:
MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50150895
n/a
NameBDBM50150895
Synonyms:(Z)-7-[(2R,3S,4R)-4-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1-enyl)-tetrahydro-furan-3-yl]-hept-5-enoic acid | CHEMBL264554
TypeSmall organic molecule
Emp. Form.C19H32O5
Mol. Mass.340.4544
SMILESCCCCC[C@@H](O)\C=C\[C@H]1OC[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Structure
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