| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin F2-alpha receptor |
|---|
| Ligand | BDBM50150897 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_310565 (CHEMBL834139) |
|---|
| EC50 | 252±n/a nM |
|---|
| Citation |  Selliah, RD; Hellberg, MR; Sharif, NA; McLaughlin, MA; Williams, GW; Scott, DA; Earnest, D; Haggard, KS; Dean, WD; Delgado, P; Gaines, MS; Conrow, RE; Klimko, PG AL-12182, a novel 11-oxa prostaglandin analog with topical ocular hypotensive activity in the monkey. Bioorg Med Chem Lett14:4525-8 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin F2-alpha receptor |
|---|
| Name: | Prostaglandin F2-alpha receptor |
|---|
| Synonyms: | PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40072.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43088 |
|---|
| Residue: | 359 |
|---|
| Sequence: | MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
|
|
|
|---|
| BDBM50150897 |
|---|
| n/a |
|---|
| Name | BDBM50150897 |
|---|
| Synonyms: | (Z)-8-[(2R,3S,4R)-4-Hydroxy-2-((E)-(S)-3-hydroxy-4-phenoxy-but-1-enyl)-tetrahydro-furan-3-yl]-oct-4-enoic acid | CHEMBL363946 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H30O6 |
|---|
| Mol. Mass. | 390.47 |
|---|
| SMILES | O[C@H](COc1ccccc1)\C=C\[C@H]1OC[C@H](O)[C@@H]1CCC\C=C/CCC(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
