| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin F2-alpha receptor |
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| Ligand | BDBM50150897 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_310565 |
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| EC50 | 252±n/a nM |
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| Citation |  Selliah RD; Hellberg MR; Sharif NA; McLaughlin MA; Williams GW; Scott DA; Earnest D; Haggard KS; Dean WD; Delgado P; Gaines MS; Conrow RE; Klimko PG AL-12182, a novel 11-oxa prostaglandin analog with topical ocular hypotensive activity in the monkey. Bioorg Med Chem Lett 14:4525-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin F2-alpha receptor |
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| Name: | Prostaglandin F2-alpha receptor |
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| Synonyms: | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40072.29 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43088 |
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| Residue: | 359 |
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| Sequence: | MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ
KSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGL
CPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQ
ASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQG
RSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILD
PWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
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| BDBM50150897 |
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| n/a |
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| Name | BDBM50150897 |
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| Synonyms: | (Z)-8-[(2R,3S,4R)-4-Hydroxy-2-((E)-(S)-3-hydroxy-4-phenoxy-but-1-enyl)-tetrahydro-furan-3-yl]-oct-4-enoic acid | CHEMBL363946 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H30O6 |
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| Mol. Mass. | 390.47 |
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| SMILES | O[C@H](COc1ccccc1)\C=C\[C@H]1OC[C@H](O)[C@@H]1CCC\C=C/CCC(O)=O |
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| Structure | 
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