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TargetSphingosine 1-phosphate receptor 1
LigandBDBM50152330
Substrate/Competitorn/a
Meas. Tech.ChEMBL_306053 (CHEMBL833009)
IC50 82±n/a nM
Citation Yan, LHale, JJLynch, CLBudhu, RGentry, AMills, SGHajdu, RKeohane, CARosenbach, MJMilligan, JAShei, GJChrebet, GBergstrom, JCard, DRosen, HMandala, SM Design and synthesis of conformationally constrained 3-(N-alkylamino)propylphosphonic acids as potent agonists of sphingosine-1-phosphate (S1P) receptors. Bioorg Med Chem Lett14:4861-6 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 1
Name:Sphingosine 1-phosphate receptor 1
Synonyms:CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:Enzyme
Mol. Mass.:42836.02
Organism:Homo sapiens (Human)
Description:P21453
Residue:382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
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BDBM50152330
n/a
NameBDBM50152330
Synonyms:(3-Tetradecylamino-cyclohexyl)-phosphonic acid | CHEMBL186921
TypeSmall organic molecule
Emp. Form.C20H42NO3P
Mol. Mass.375.5261
SMILESCCCCCCCCCCCCCCNC1CCCC(C1)P(O)(O)=O
Structure
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