| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 4 |
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| Ligand | BDBM50152538 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304397 (CHEMBL830047) |
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| EC50 | 48±n/a nM |
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| Citation |  Clemens, JJ; Davis, MD; Lynch, KR; Macdonald, TL Synthesis of benzimidazole based analogues of sphingosine-1-phosphate: discovery of potent, subtype-selective S1P4 receptor agonists. Bioorg Med Chem Lett14:4903-6 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 4 |
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| Name: | Sphingosine 1-phosphate receptor 4 |
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| Synonyms: | EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41647.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 384 |
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| Sequence: | MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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| BDBM50152538 |
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| n/a |
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| Name | BDBM50152538 |
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| Synonyms: | CHEMBL185491 | Phosphoric acid mono-[(R)-2-amino-2-(6-octyl-1H-benzoimidazol-2-yl)-ethyl] ester; TFA methyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C17H28N3O4P |
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| Mol. Mass. | 369.3957 |
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| SMILES | CCCCCCCCc1ccc2nc([nH]c2c1)[C@@H](N)COP(O)(O)=O |
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| Structure | 
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