| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase |
|---|
| Ligand | BDBM10871 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_303240 (CHEMBL827205) |
|---|
| Ki | 180±n/a nM |
|---|
| Citation |  Zimmerman, S; Innocenti, A; Casini, A; Ferry, JG; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides. Bioorg Med Chem Lett14:6001-6 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase |
|---|
| Name: | Carbonic anhydrase |
|---|
| Synonyms: | CAH_METTT | CAM | Carbonic anhydrase | Gamma-carbonic anhydrase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 26390.56 |
|---|
| Organism: | Methanosarcina thermophila |
|---|
| Description: | P40881 |
|---|
| Residue: | 247 |
|---|
| Sequence: | MMFNKQIFTILILSLSLALAGSGCISEGAEDNVAQEITVDEFSNIRENPVTPWNPEPSAP
VIDPTAYIDPQASVIGEVTIGANVMVSPMASIRSDEGMPIFVGDRSNVQDGVVLHALETI
NEEGEPIEDNIVEVDGKEYAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGN
NCVLEPRSAAIGVTIPDGRYIPAGMVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNVHLA
EGYKETS
|
|
|
|---|
| BDBM10871 |
|---|
| n/a |
|---|
| Name | BDBM10871 |
|---|
| Synonyms: | 4-amino-N-[(4-sulfamoylphenyl)methyl]benzene-1-sulfonamide | CHEMBL266026 | aromatic/heteroaromatic sulfonamide 16 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H15N3O4S2 |
|---|
| Mol. Mass. | 341.406 |
|---|
| SMILES | Nc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)S(N)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
