| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase |
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| Ligand | BDBM10866 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303239 (CHEMBL827204) |
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| Ki | 950±n/a nM |
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| Citation |  Zimmerman, S; Innocenti, A; Casini, A; Ferry, JG; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides. Bioorg Med Chem Lett14:6001-6 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase |
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| Name: | Carbonic anhydrase |
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| Synonyms: | CAH_METTT | CAM | Carbonic anhydrase | Gamma-carbonic anhydrase |
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| Type: | Protein |
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| Mol. Mass.: | 26390.56 |
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| Organism: | Methanosarcina thermophila |
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| Description: | P40881 |
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| Residue: | 247 |
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| Sequence: | MMFNKQIFTILILSLSLALAGSGCISEGAEDNVAQEITVDEFSNIRENPVTPWNPEPSAP
VIDPTAYIDPQASVIGEVTIGANVMVSPMASIRSDEGMPIFVGDRSNVQDGVVLHALETI
NEEGEPIEDNIVEVDGKEYAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGN
NCVLEPRSAAIGVTIPDGRYIPAGMVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNVHLA
EGYKETS
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| BDBM10866 |
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| n/a |
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| Name | BDBM10866 |
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| Synonyms: | 4-amino-6-(trifluoromethyl)benzene-1,3-disulfonamide | CHEMBL418 | aromatic/heteroaromatic sulfonamide 11 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H8F3N3O4S2 |
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| Mol. Mass. | 319.281 |
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| SMILES | Nc1cc(c(cc1S(N)(=O)=O)S(N)(=O)=O)C(F)(F)F |
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| Structure | 
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