| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50166745 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303806 (CHEMBL829027) |
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| Ki | 62±n/a nM |
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| Citation |  Press, NJ; Taylor, RJ; Fullerton, JD; Tranter, P; McCarthy, C; Keller, TH; Brown, L; Cheung, R; Christie, J; Haberthuer, S; Hatto, JD; Keenan, M; Mercer, MK; Press, NE; Sahri, H; Tuffnell, AR; Tweed, M; Fozard, JR A new orally bioavailable dual adenosine A2B/A3 receptor antagonist with therapeutic potential. Bioorg Med Chem Lett15:3081-5 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50166745 |
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| n/a |
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| Name | BDBM50166745 |
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| Synonyms: | 3-[2-(Pyridin-4-ylamino)-5-[1,2,4]triazol-1-yl-thiazol-4-yl]-benzonitrile | CHEMBL365172 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H11N7S |
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| Mol. Mass. | 345.381 |
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| SMILES | N#Cc1cccc(c1)-c1nc(Nc2ccncc2)sc1-n1cncn1 |
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| Structure | 
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