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TargetCarbonic anhydrase 1
LigandBDBM50167327
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302302
Ki 35±n/a nM
Citation Garaj VPuccetti LFasolis GWinum JYMontero JLScozzafava AVullo DInnocenti ASupuran CT Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX. Bioorg Med Chem Lett 15:3102-8 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 1
Name:Carbonic anhydrase
Synonyms:CA-I | CAB | Carbonate dehydratase I | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:Enzyme
Mol. Mass.:28873.37
Organism:Homo sapiens (Human)
Description:P00915
Residue:261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
PMQHNNRPTQPLKGRTVRASF
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BDBM50167327
n/a
NameBDBM50167327
Synonyms:CHEMBL191045 | [4-Chloro-6-(4-sulfamoyl-benzylamino)-[1,3,5]triazin-2-ylamino]-acetic acid
TypeSmall organic molecule
Emp. Form.C12H13ClN6O4S
Mol. Mass.372.787
SMILESNS(=O)(=O)c1ccc(CNc2nc(Cl)nc(NCC(O)=O)n2)cc1
Structure
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