| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
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| Ligand | BDBM50159775 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302794 (CHEMBL839478) |
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| Ki | >9000±n/a nM |
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| Citation |  Belley, M; Gallant, M; Roy, B; Houde, K; Lachance, N; Labelle, M; Trimble, LA; Chauret, N; Li, C; Sawyer, N; Tremblay, N; Lamontagne, S; Carrière, MC; Denis, D; Greig, GM; Slipetz, D; Metters, KM; Gordon, R; Chan, CC; Zamboni, RJ Structure-activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP(3) antagonists. Bioorg Med Chem Lett15:527-30 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP1 subtype |
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| Name: | Prostaglandin E2 receptor EP1 subtype |
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| Synonyms: | PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41834.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34995 |
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| Residue: | 402 |
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| Sequence: | MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
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| BDBM50159775 |
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| n/a |
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| Name | BDBM50159775 |
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| Synonyms: | 3-{2-[2-(2-Benzyloxy-3-methyl-phenyl)-cyclopropyl]-phenyl}-propionic acid | CHEMBL180752 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26O3 |
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| Mol. Mass. | 386.4828 |
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| SMILES | Cc1cccc(C2CC2c2ccccc2CCC(O)=O)c1OCc1ccccc1 |
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| Structure | 
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