| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM50160673 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302350 (CHEMBL828071) |
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| Ki | 7±n/a nM |
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| Citation |  Vullo, D; Voipio, J; Innocenti, A; Rivera, C; Ranki, H; Scozzafava, A; Kaila, K; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. Bioorg Med Chem Lett15:971-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM50160673 |
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| n/a |
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| Name | BDBM50160673 |
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| Synonyms: | 5-(4-Amino-benzenesulfonylamino)-4,5-dihydro-[1,3,4]thiadiazole-2-sulfonic acid amide | CHEMBL427312 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H11N5O4S3 |
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| Mol. Mass. | 337.399 |
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| SMILES | Nc1ccc(cc1)S(=O)(=O)NC1=NNC(S1)S(N)(=O)=O |t:12| |
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| Structure | 
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