| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
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| Ligand | BDBM10881 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302395 (CHEMBL840830) |
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| Ki | 19±n/a nM |
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| Citation |  Vullo, D; Voipio, J; Innocenti, A; Rivera, C; Ranki, H; Scozzafava, A; Kaila, K; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. Bioorg Med Chem Lett15:971-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 13 |
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| Name: | Carbonic anhydrase 13 |
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| Synonyms: | CA-XIII | CAH13_MOUSE | Ca13 | Car13 | Carbonate dehydratase XIII | Carbonic anhydrase 13 | Carbonic anhydrase XIII |
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| Type: | Enzyme |
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| Mol. Mass.: | 29522.80 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Murine cloned isozyme |
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| Residue: | 262 |
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| Sequence: | MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKII
SNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELH
VVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNF
DPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAA
FLLSNHRPPQPLKGRRVRASFY
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| BDBM10881 |
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| n/a |
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| Name | BDBM10881 |
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| Synonyms: | CHEMBL288100 | MZA3 | Methazolamide | Methazolamide (MZA) | Methazolamide, MZA | N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide | Sulfonamide, 2 | cid_4100 | sulfonamide 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H8N4O3S2 |
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| Mol. Mass. | 236.272 |
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| SMILES | CC(=O)N=c1sc(nn1C)S(N)(=O)=O |w:3.2| |
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| Structure | 
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