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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Ligand | BDBM50164913 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_303552 (CHEMBL828952) | ||
| Ki | 7±n/a nM | ||
| Citation |  Mazurov, A; Klucik, J; Miao, L; Phillips, TY; Seamans, A; Schmitt, JD; Hauser, TA; Johnson, RT; Miller, C 2-(Arylmethyl)-3-substituted quinuclidines as selective alpha 7 nicotinic receptor ligands. Bioorg Med Chem Lett15:2073-7 (2005) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuronal acetylcholine receptor subunit alpha-7 | |||
| Name: | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Synonyms: | ACHA7_RAT | Acra7 | Cholinergic, Nicotinic Alpha7 | Cholinergic, Nicotinic Alpha7/5-HT3 | Chrna7 | Neuronal acetylcholine receptor | Neuronal acetylcholine receptor (alpha7 nAChR) | Neuronal acetylcholine receptor subunit alpha 7 | Neuronal acetylcholine receptor subunit alpha-7 | Neuronal acetylcholine receptor subunit alpha-7 (nAChR alpha7) | Neuronal acetylcholine receptor subunit alpha-7 (nAChR) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 56502.44 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | Q05941 | ||
| Residue: | 502 | ||
| Sequence: |
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| BDBM50164913 | |||
| n/a | |||
| Name | BDBM50164913 | ||
| Synonyms: | 4-Bromo-N-((2R,3R)-2-pyridin-3-ylmethyl-1-aza-bicyclo[2.2.2]oct-3-yl)-benzamide | CHEMBL370523 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H22BrN3O | ||
| Mol. Mass. | 400.312 | ||
| SMILES | Brc1ccc(cc1)C(=O)N[C@@H]1C2CCN(CC2)[C@@H]1Cc1cccnc1 |wU:10.10,17.20,(14.57,4.83,;13.24,4.06,;11.9,4.83,;10.57,4.06,;10.57,2.53,;11.9,1.75,;13.24,2.52,;9.24,1.75,;9.24,.21,;7.9,2.54,;6.55,1.77,;5.22,2.54,;4.45,1.21,;5.78,.44,;5.22,-.55,;3.9,.23,;3.9,1.77,;6.55,.23,;7.9,-.55,;7.89,-2.09,;6.55,-2.86,;6.55,-4.4,;7.89,-5.18,;9.24,-4.4,;9.22,-2.86,)| | ||
| Structure | 
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