| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
|---|
| Ligand | BDBM50151214 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_302248 (CHEMBL830264) |
|---|
| Kd | 22±n/a nM |
|---|
| Citation |  Tahtaoui, C; Parrot, I; Klotz, P; Guillier, F; Galzi, JL; Hibert, M; Ilien, B Fluorescent pirenzepine derivatives as potential bitopic ligands of the human M1 muscarinic receptor. J Med Chem47:4300-15 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Muscarinic acetylcholine receptor M1 |
|---|
| Name: | Muscarinic acetylcholine receptor M1 |
|---|
| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 51442.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P11229 |
|---|
| Residue: | 460 |
|---|
| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
|
|
|
|---|
| BDBM50151214 |
|---|
| n/a |
|---|
| Name | BDBM50151214 |
|---|
| Synonyms: | CHEMBL2368390 | difluoro(2-{[(2Z)-1-methyl-5-[2-({20-[4-(2-oxo-2-{10-oxo-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}ethyl)piperazin-1-yl]-3,6,9,12,15,18-hexaoxaicosan-1-yl}carbamoyl)ethyl]-2H-pyrrol-1-ium-2-ylidene]methyl}-5-(thiophen-2-yl)-1H-pyrrol-1-yl)boranuide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C40H43BF2N8O5S |
|---|
| Mol. Mass. | 796.693 |
|---|
| SMILES | F[B-]1(F)n2c(ccc2-c2cccs2)C=C2C=CC(CCC(=O)NCCOCCOCCN3CCN(CC(=O)N4c5ccccc5C(=O)Nc5cccnc45)CC3)=[N+]12 |c:17,t:15,61| |
|---|
| Structure | 
|
|---|
Search and Browse
