| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50152075 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303007 (CHEMBL830246) |
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| Ki | 10±n/a nM |
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| Citation |  Elzein, E; Palle, V; Wu, Y; Maa, T; Zeng, D; Zablocki, J 2-Pyrazolyl-N(6)-substituted adenosine derivatives as high affinity and selective adenosine A(3) receptor agonists. J Med Chem47:4766-73 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50152075 |
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| n/a |
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| Name | BDBM50152075 |
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| Synonyms: | 2-{2-[4-(4-Chloro-phenyl)-pyrazol-1-yl]-6-methylamino-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol | CHEMBL365642 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20ClN7O4 |
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| Mol. Mass. | 457.87 |
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| SMILES | CNc1nc(nc2n(cnc12)C1O[C@H](CO)[C@@H](O)[C@H]1O)-n1cc(cn1)-c1ccc(Cl)cc1 |
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| Structure | 
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