| Reaction Details |
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 | Report a problem with these data |
| Target | MO15-related protein kinase Pfmrk |
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| Ligand | BDBM22985 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_306159 (CHEMBL832347) |
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| IC50 | 150000±n/a nM |
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| Citation |  Bhattacharjee, AK; Geyer, JA; Woodard, CL; Kathcart, AK; Nichols, DA; Prigge, ST; Li, Z; Mott, BT; Waters, NC A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors. J Med Chem47:5418-26 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| MO15-related protein kinase Pfmrk |
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| Name: | MO15-related protein kinase Pfmrk |
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| Synonyms: | Protein kinase Pfmrk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37992.30 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_640752 |
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| Residue: | 324 |
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| Sequence: | MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLL
REIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQI
LNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLN
LTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFL
LGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAED
AMKHRYFFNDPLPCDISQLPFNDL
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| BDBM22985 |
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| n/a |
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| Name | BDBM22985 |
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| Synonyms: | Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chlorochin | Chloroquine | Chloroquine, 17 | med.21724, Compound 8 | {4-[(7-chloroquinolin-4-yl)amino]pentyl}diethylamine |
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| Type | Antimalarial |
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| Emp. Form. | C18H26ClN3 |
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| Mol. Mass. | 319.872 |
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| SMILES | CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 |
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| Structure | 
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