Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50156139 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_302776 (CHEMBL838839) |
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Ki | 5000±n/a nM |
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Citation | Shuman, CF; Vrang, L; Danielson, UH Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data. J Med Chem47:5953-61 (2004) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50156139 |
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n/a |
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Name | BDBM50156139 |
Synonyms: | 3,4-Dihydroxy-1,6-bis-[3-(4-hydroxy-phenyl)-2-methyl-propionylamino]-1,6-dioxo-5-phenoxy-hexan-2-ol anion |
Type | Small organic molecule |
Emp. Form. | C32H35N2O10 |
Mol. Mass. | 607.6282 |
SMILES | C[C@@H](Cc1ccc(O)cc1)C(=O)NC(=O)[C@H]([O-])[C@H](O)[C@@H](O)[C@@H](Oc1ccccc1)C(=O)NC(=O)[C@@H](C)Cc1ccc(O)cc1 |
Structure |
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