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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50156147
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302776
Ki 0.05±n/a nM
Citation Shuman CFVrang LDanielson UH Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data. J Med Chem 47:5953-61 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50156147
n/a
NameBDBM50156147
Synonyms:1-(2,3-Dimethyl-butyrylamino)-3,4-dihydroxy-5-(2-hydroxy-indan-1-ylcarbamoyl)-1-oxo-5-phenoxy-pentan-2-ol anion
TypeSmall organic molecule
Emp. Form.C27H33N2O8
Mol. Mass.513.5601
SMILESCC(C)[C@H](C)C(=O)NC(=O)[C@H]([O-])[C@H](O)[C@@H](O)[C@@H](Oc1ccccc1)C(=O)NC1[C@@H](O)Cc2ccccc12
Structure
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