| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50156145 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302137 (CHEMBL841761) |
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| Kd | 169±n/a nM |
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| Citation |  Shuman, CF; Vrang, L; Danielson, UH Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data. J Med Chem47:5953-61 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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| BDBM50156145 |
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| n/a |
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| Name | BDBM50156145 |
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| Synonyms: | 2,7-Bis-[3-(1-hydroxyamino-ethyl)-benzyl]-1,1-dioxo-3,6-bis-phenoxymethyl-1lambda*6*-[1,2,7]thiadiazepane-4,5-diol | CHEMBL190112 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H44N4O8S |
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| Mol. Mass. | 692.822 |
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| SMILES | CC(NO)c1cccc(CN2[C@H](COc3ccccc3)[C@H](O)[C@@H](O)[C@@H](COc3ccccc3)N(Cc3cccc(c3)C(C)NO)S2(=O)=O)c1 |
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| Structure | 
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