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TargetGag-Pol polyprotein [489-587]
LigandBDBM50156153
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302137 (CHEMBL841761)
Kd 18.2±n/a nM
Citation Shuman, CFVrang, LDanielson, UH Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data. J Med Chem47:5953-61 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50156153
n/a
NameBDBM50156153
Synonyms:1,6-Bis-(2,3-dimethyl-butyrylamino)-3,4-dihydroxy-5-(3''-nitro-biphenyl-4-yloxy)-1,6-dioxo-hexan-2-ol anion
TypeSmall organic molecule
Emp. Form.C30H38N3O10
Mol. Mass.600.6374
SMILESCC(C)[C@H](C)C(=O)NC(=O)[C@H]([O-])[C@H](O)[C@@H](O)[C@@H](Oc1ccc(cc1)-c1cccc(c1)[N+]([O-])=O)C(=O)NC(=O)[C@@H](C)C(C)C
Structure
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