Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50156155 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_302776 (CHEMBL838839) |
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Ki | 0.8±n/a nM |
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Citation | Shuman, CF; Vrang, L; Danielson, UH Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data. J Med Chem47:5953-61 (2004) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50156155 |
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n/a |
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Name | BDBM50156155 |
Synonyms: | 1,6-Bis-(2,3-dimethyl-butyrylamino)-3,4-dihydroxy-1,6-dioxo-5-(4-phenethyl-phenoxy)-hexan-2-ol anion |
Type | Small organic molecule |
Emp. Form. | C32H43N2O8 |
Mol. Mass. | 583.693 |
SMILES | CC(C)[C@H](C)C(=O)NC(=O)[C@H]([O-])[C@H](O)[C@@H](O)[C@@H](Oc1ccc(CCc2ccccc2)cc1)C(=O)NC(=O)[C@@H](C)C(C)C |
Structure |
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