| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(3) dopamine receptor |
|---|
| Ligand | BDBM50071959 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_303000 (CHEMBL830239) |
|---|
| Ki | 1.1±n/a nM |
|---|
| Citation |  Newman, AH; Grundt, P; Nader, MA Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. J Med Chem48:3663-79 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(3) dopamine receptor |
|---|
| Name: | D(3) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 49540.58 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P19020 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC
|
|
|
|---|
| BDBM50071959 |
|---|
| n/a |
|---|
| Name | BDBM50071959 |
|---|
| Synonyms: | 9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide | CHEMBL300780 | N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H29Cl2N3O |
|---|
| Mol. Mass. | 494.455 |
|---|
| SMILES | Clc1cccc(N2CCN(CCCCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
