| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 15 member 1 |
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| Ligand | BDBM50169134 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302952 (CHEMBL841787) |
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| Ki | 110000±n/a nM |
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| Citation |  Biegel, A; Gebauer, S; Hartrodt, B; Brandsch, M; Neubert, K; Thondorf, I Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1. J Med Chem48:4410-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 15 member 1 |
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| Name: | Solute carrier family 15 member 1 |
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| Synonyms: | Intestinal H(+)/peptide cotransporter | Oligopeptide transporter small intestine isoform | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_HUMAN | SLC15A1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78818.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1488839 |
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| Residue: | 708 |
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| Sequence: | MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFV
ALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPV
HVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTII
TPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCI
GFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQ
GSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKK
MAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGP
MSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQK
PEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQ
PNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSV
TGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVC
VIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
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| BDBM50169134 |
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| n/a |
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| Name | BDBM50169134 |
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| Synonyms: | (S)-2-((S)-2-Amino-3-phenyl-propionylamino)-3-phenyl-propionic acid | 2-(2-Amino-3-phenyl-propionylamino)-3-phenyl-propionic acid | CHEMBL55868 | H-Phe-Phe-OH | I(S)-2-((S)-2-Amino-3-phenyl-propionylaIImino)-3-phenyl-propionic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N2O3 |
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| Mol. Mass. | 312.363 |
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| SMILES | N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |
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| Structure | 
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