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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50170660
Substrate/Competitorn/a
Meas. Tech.ChEMBL_303441 (CHEMBL839610)
Ki 1±n/a nM
Citation Laggner, CSchieferer, CFiechtner, BPoles, GHoffmann, RDGlossmann, HLanger, TMoebius, FF Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening. J Med Chem48:4754-64 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:Enzyme Catalytic Domain
Mol. Mass.:25124.85
Organism:Homo sapiens (Human)
Description:Q99720
Residue:223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50170660
n/a
NameBDBM50170660
Synonyms:CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine | N-(4-methoxy-3-phenethoxyphenethyl)-N-propylpropan-1-amine | NE-100 | [2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-dipropyl-amine
TypeSmall organic molecule
Emp. Form.C23H33NO2
Mol. Mass.355.5136
SMILESCCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1
Structure
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