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TargetC-8 sterol isomerase
LigandBDBM20607
Substrate/Competitorn/a
Meas. Tech.ChEMBL_303390
Ki 1500±n/a nM
Citation Laggner CSchieferer CFiechtner BPoles GHoffmann RDGlossmann HLanger TMoebius FF Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening. J Med Chem 48:4754-64 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C-8 sterol isomerase
Name:C-8 sterol isomerase
Synonyms:Delta-8--delta-7 sterol isomerase
Type:PROTEIN
Mol. Mass.:24892.29
Organism:Saccharomyces cerevisiae
Description:ChEMBL_303390
Residue:222
Sequence:
MKFFPLLLLIGVVGYIMNVLFTTWLPTNYMFDPKTLNEICNSVISKHNAAEGLSTEDLLQ
DVRDALASHYGDEYINRYVKEEWVFNNAGGAMGQMIILHASVSEYLILFGTAVGTEGHTG
VHFADDYFTILHGTQIAALPYATEAEVYTPGMTHHLKKGYAKQYSMPGGSFALELAQGWI
PCMLPFGFLDTFSSTLDLYTLYRTVYLTARDMGKNLLQNKKF
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  Blast E-value cutoff:
BDBM20607
n/a
NameBDBM20607
Synonyms:(2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine | 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine | CHEMBL83 | FOSTRIECIN SODIUM | NCGC00024928 | Nolvadex | Tamoxifen | Tamoxifen (8) | Tamoxifen, 7 | cid_2733526
TypeSmall organic molecule
Emp. Form.C26H29NO
Mol. Mass.371.5146
SMILESCC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Structure
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