| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amiloride-sensitive amine oxidase [copper-containing] |
|---|
| Ligand | BDBM50161153 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_306517 (CHEMBL828122) |
|---|
| IC50 | 120±n/a nM |
|---|
| Citation |  Bertini, V; Buffoni, F; Ignesti, G; Picci, N; Trombino, S; Iemma, F; Alfei, S; Pocci, M; Lucchesini, F; De Munno, A Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases. J Med Chem48:664-70 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amiloride-sensitive amine oxidase [copper-containing] |
|---|
| Name: | Amiloride-sensitive amine oxidase [copper-containing] |
|---|
| Synonyms: | ABP | ABP1 | AOC1 | AOC1_HUMAN | Amiloride-binding protein | DAO | DAO1 | Diamine oxidase | Diamine oxidase (DAO) | Histaminase | KAO | Kidney amine oxidase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 85387.64 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P19801 |
|---|
| Residue: | 751 |
|---|
| Sequence: | MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSS
TTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLP
GPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR
CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNG
KFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGP
RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYG
GHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE
MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMH
ATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENIT
NPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSM
ADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENI
ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRD
NGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
|
|
|
|---|
| BDBM50161153 |
|---|
| n/a |
|---|
| Name | BDBM50161153 |
|---|
| Synonyms: | 4-(aminomethyl)-N-methyl-5-(methyl-lambda~5~-azanyl)pyridin-3-amine dihydrochloride | CHEMBL537845 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H14N4 |
|---|
| Mol. Mass. | 166.2236 |
|---|
| SMILES | CNc1cncc(NC)c1CN |
|---|
| Structure | 
|
|---|
Search and Browse
