| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Solute carrier family 15 member 1 |
|---|
| Ligand | BDBM50162073 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_306462 (CHEMBL829539) |
|---|
| IC50 | 431000±n/a nM |
|---|
| Citation |  Song, X; Vig, BS; Lorenzi, PL; Drach, JC; Townsend, LB; Amidon, GL Amino acid ester prodrugs of the antiviral agent 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole as potential substrates of hPEPT1 transporter. J Med Chem48:1274-7 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Solute carrier family 15 member 1 |
|---|
| Name: | Solute carrier family 15 member 1 |
|---|
| Synonyms: | Intestinal H(+)/peptide cotransporter | Oligopeptide transporter small intestine isoform | Oligopeptide transporter, small intestine isoform | PEPT1 | Peptide transporter 1 | S15A1_HUMAN | SLC15A1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 78818.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1488839 |
|---|
| Residue: | 708 |
|---|
| Sequence: | MGMSKSHSFFGYPLSIFFIVVNEFCERFSYYGMRAILILYFTNFISWDDNLSTAIYHTFV
ALCYLTPILGALIADSWLGKFKTIVSLSIVYTIGQAVTSVSSINDLTDHNHDGTPDSLPV
HVVLSLIGLALIALGTGGIKPCVSAFGGDQFEEGQEKQRNRFFSIFYLAINAGSLLSTII
TPMLRVQQCGIHSKQACYPLAFGVPAALMAVALIVFVLGSGMYKKFKPQGNIMGKVAKCI
GFAIKNRFRHRSKAFPKREHWLDWAKEKYDERLISQIKMVTRVMFLYIPLPMFWALFDQQ
GSRWTLQATTMSGKIGALEIQPDQMQTVNAILIVIMVPIFDAVLYPLIAKCGFNFTSLKK
MAVGMVLASMAFVVAAIVQVEIDKTLPVFPKGNEVQIKVLNIGNNTMNISLPGEMVTLGP
MSQTNAFMTFDVNKLTRINISSPGSPVTAVTDDFKQGQRHTLLVWAPNHYQVVKDGLNQK
PEKGENGIRFVNTFNELITITMSGKVYANISSYNASTYQFFPSGIKGFTISSTEIPPQCQ
PNFNTFYLEFGSAYTYIVQRKNDSCPEVKVFEDISANTVNMALQIPQYFLLTCGEVVFSV
TGLEFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAGAGQFSKQWAEYILFAALLLVVC
VIFAIMARFYTYINPAEIEAQFDEDEKKNRLEKSNPYFMSGANSQKQM
|
|
|
|---|
| BDBM50162073 |
|---|
| n/a |
|---|
| Name | BDBM50162073 |
|---|
| Synonyms: | (S)-2-((2-amino-6-oxo-3H-purin-9(6H)-yl)methoxy)ethyl 2-amino-3-methylbutanoate | (S)-2-Amino-3-methyl-butyric acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester | CHEMBL1349 | VALACYCLOVIR |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H20N6O4 |
|---|
| Mol. Mass. | 324.3357 |
|---|
| SMILES | CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1nc(N)[nH]c2=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
