| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
|---|
| Ligand | BDBM50166126 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_304147 (CHEMBL840263) |
|---|
| EC50 | 26.6±n/a nM |
|---|
| Citation |  Todorovic, A; Holder, JR; Bauzo, RM; Scott, JW; Kavanagh, R; Abdel-Malek, Z; Haskell-Luevano, C N-terminal fatty acylated His-dPhe-Arg-Trp-NH(2) tetrapeptides: influence of fatty acid chain length on potency and selectivity at the mouse melanocortin receptors and human melanocytes. J Med Chem48:3328-36 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocortin receptor 4 |
|---|
| Name: | Melanocortin receptor 4 |
|---|
| Synonyms: | MC4-R | MC4R_MOUSE | Mc4r |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36964.43 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1498850 |
|---|
| Residue: | 332 |
|---|
| Sequence: | MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVS
GVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTN
MKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPL
IYALRSQELRKTFKEIICFYPLGGICELSSRY
|
|
|
|---|
| BDBM50166126 |
|---|
| n/a |
|---|
| Name | BDBM50166126 |
|---|
| Synonyms: | CHEMBL265236 | Hexadecanoic acid [(S)-1-((R)-1-{(S)-1-[(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-4-guanidino-butylcarbamoyl}-2-phenyl-ethylcarbamoyl)-2-(3H-imidazol-4-yl)-ethyl]-amide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C48H71N11O5 |
|---|
| Mol. Mass. | 882.148 |
|---|
| SMILES | CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
