| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 2b |
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| Ligand | BDBM50134805 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305568 (CHEMBL827162) |
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| IC50 | 10±n/a nM |
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| Citation |  Mai, A; Massa, S; Pezzi, R; Simeoni, S; Rotili, D; Nebbioso, A; Scognamiglio, A; Altucci, L; Loidl, P; Brosch, G Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides. J Med Chem48:3344-53 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 2b |
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| Name: | Histone deacetylase 2b |
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| Synonyms: | Histone deacetylase HD2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30785.07 |
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| Organism: | Zea mays |
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| Description: | ChEMBL_87549 |
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| Residue: | 286 |
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| Sequence: | MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVE
KHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQN
NEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEM
SEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSE
QSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
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| BDBM50134805 |
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| n/a |
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| Name | BDBM50134805 |
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| Synonyms: | 6,9-Dibenzyl-12-(6-oxiranyl-6-oxo-hexyl)-decahydro-4a,7,10,13-tetraaza-benzocyclododecene-5,8,11,14-tetraone | CHEMBL274445 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H42N4O6 |
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| Mol. Mass. | 602.7205 |
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| SMILES | O=C(CCCCC[C@@H]1NC(=O)[C@H]2CCCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC1=O)C1CO1 |
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| Structure | 
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