| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-S-isoprenylcysteine O-methyltransferase |
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| Ligand | BDBM50174225 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_320848 (CHEMBL884633) |
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| Ki | 4600±n/a nM |
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| Citation |  Henriksen, BS; Anderson, JL; Hrycyna, CA; Gibbs, RA Synthesis of desthio prenylcysteine analogs: sulfur is important for biological activity. Bioorg Med Chem Lett15:5080-3 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-S-isoprenylcysteine O-methyltransferase |
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| Name: | Protein-S-isoprenylcysteine O-methyltransferase |
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| Synonyms: | Isoprenylcysteine carboxyl methyltransferase | STE14 | STE14_YEAST |
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| Type: | PROTEIN |
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| Mol. Mass.: | 27893.87 |
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| Organism: | Saccharomyces cerevisiae |
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| Description: | ChEMBL_321482 |
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| Residue: | 239 |
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| Sequence: | MHQDFQEDEHEYPDIRRNPLHEVTMTSYILGILLGIFVGLFPQIRFKNFNLFIIALSLFH
FLEYYITAKYNPLKVHSESFLLNNGKSYMAAHSFAILECLVESFLFPDLKIFSYSLATKL
CTVLGCLLVILGQYTRTIAMHTAGHSFSHIVKTKKESDHVLVKTGVYSWSRHPSYLGFFW
WAIGTQLLLLNPLSLVIFIFVLWKFFSDRIRVEEKYLIEFFSAEYIEYKNKVGVGIPFI
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| BDBM50174225 |
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| n/a |
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| Name | BDBM50174225 |
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| Synonyms: | ((2E,6E)-3,7,11-Trimethyl-dodeca-2,6,10-trienylsulfanyl)-acetic acid anion |
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| Type | Small organic molecule |
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| Emp. Form. | C17H27O2S |
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| Mol. Mass. | 295.461 |
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| SMILES | [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#16]-[#6]-[#6](-[#8-])=O |
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| Structure | 
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