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TargetProtein-S-isoprenylcysteine O-methyltransferase
LigandBDBM50174226
Substrate/Competitorn/a
Meas. Tech.ChEMBL_320848 (CHEMBL884633)
Ki 13200±n/a nM
Citation Henriksen, BSAnderson, JLHrycyna, CAGibbs, RA Synthesis of desthio prenylcysteine analogs: sulfur is important for biological activity. Bioorg Med Chem Lett15:5080-3 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Protein-S-isoprenylcysteine O-methyltransferase
Name:Protein-S-isoprenylcysteine O-methyltransferase
Synonyms:Isoprenylcysteine carboxyl methyltransferase | STE14 | STE14_YEAST
Type:PROTEIN
Mol. Mass.:27893.87
Organism:Saccharomyces cerevisiae
Description:ChEMBL_321482
Residue:239
Sequence:
MHQDFQEDEHEYPDIRRNPLHEVTMTSYILGILLGIFVGLFPQIRFKNFNLFIIALSLFH
FLEYYITAKYNPLKVHSESFLLNNGKSYMAAHSFAILECLVESFLFPDLKIFSYSLATKL
CTVLGCLLVILGQYTRTIAMHTAGHSFSHIVKTKKESDHVLVKTGVYSWSRHPSYLGFFW
WAIGTQLLLLNPLSLVIFIFVLWKFFSDRIRVEEKYLIEFFSAEYIEYKNKVGVGIPFI
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  Blast E-value cutoff:
BDBM50174226
n/a
NameBDBM50174226
Synonyms:2-acetamido-3-[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraene-1-sulfinyl]propanoate | Prenylcysteine derivative
TypeSmall organic molecule
Emp. Form.C25H40NO4S
Mol. Mass.450.655
SMILES[#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]S(=O)[#6]-[#6](-[#7]-[#6](-[#6])=O)-[#6](-[#8-])=O
Structure
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