| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50172507 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_320976 (CHEMBL885383) |
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| Ki | 6.1±n/a nM |
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| Citation |  Elsner, J; Boeckler, F; Heinemann, FW; Hübner, H; Gmeiner, P Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists. J Med Chem48:5771-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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|
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| BDBM50172507 |
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| n/a |
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| Name | BDBM50172507 |
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| Synonyms: | (3-Chloro-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-5-yl)-dipropyl-amine | CHEMBL194099 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H22ClN3 |
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| Mol. Mass. | 255.787 |
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| SMILES | CCCN(CCC)C1CCn2ncc(Cl)c2C1 |
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| Structure | 
|
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