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TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase
LigandBDBM50173563
Substrate/Competitorn/a
Meas. Tech.ChEMBL_320965 (CHEMBL885372)
Ki 12000±n/a nM
Citation Nguyen, CKasinathan, GLeal-Cortijo, IMusso-Buendia, AKaiser, MBrun, RRuiz-Pérez, LMJohansson, NGGonzález-Pacanowska, DGilbert, IH Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. J Med Chem48:5942-54 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Name:Deoxyuridine 5'-triphosphate nucleotidohydrolase
Synonyms:dUTP pyrophosphatase
Type:Protein
Mol. Mass.:19574.43
Organism:Plasmodium falciparum
Description:Q8II92
Residue:173
Sequence:
MHLKIVCLSDEVREMYKNHKTHHEGDSGLDLFIVKDEVLKPKSTTFVKLGIKAIALQYKS
NYYYKCEKSENKKKDDDKSNIVNTSFLLFPRSSISKTPLRLANSIGLIDAGYRGEIIAAL
DNTSDQEYHIKKNDKLVQLVSFTGEPLSFELVEELDETSRGEGGFGSTSNNKY
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BDBM50173563
n/a
NameBDBM50173563
Synonyms:1-{4-Fluoro-5-[(trityl-amino)-methyl]-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione | CHEMBL198660
TypeSmall organic molecule
Emp. Form.C28H26FN3O3
Mol. Mass.471.5227
SMILESFC1CC(OC1CNC(c1ccccc1)(c1ccccc1)c1ccccc1)n1ccc(=O)[nH]c1=O
Structure
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