| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Putative deoxyuridine triphosphatase |
|---|
| Ligand | BDBM50173563 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_320883 (CHEMBL884808) |
|---|
| Ki | >1000000±n/a nM |
|---|
| Citation |  Nguyen, C; Kasinathan, G; Leal-Cortijo, I; Musso-Buendia, A; Kaiser, M; Brun, R; Ruiz-Pérez, LM; Johansson, NG; González-Pacanowska, D; Gilbert, IH Deoxyuridine triphosphate nucleotidohydrolase as a potential antiparasitic drug target. J Med Chem48:5942-54 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Putative deoxyuridine triphosphatase |
|---|
| Name: | Putative deoxyuridine triphosphatase |
|---|
| Synonyms: | dUTP pyrophosphatase | dUTPase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 30347.26 |
|---|
| Organism: | Leishmania major |
|---|
| Description: | ChEMBL_320883 |
|---|
| Residue: | 268 |
|---|
| Sequence: | MKRARSANIPGAILHSLAELQDGLNAMIDPSWRAVRSLDNWALAITMESTELLDSYPWKW
WKNLNATPDLANVRIELVDIFHFSLSGAMQMRSTPDDEIPAASLKPLKEVMTTFLPAKEC
TSDPYGFVFFPLTDTQNAIASFRNIIQLANAYRFDVIIECIIYAAEDLGFNLVAYYIAKH
TLNCIRQLSGYKDGSYVKVNNGVEDNSLLHNCIKDVSLDEVLDADKYVQAWNSIMANVYE
AFQIKESDRKDAERWFALAKENRLAIKA
|
|
|
|---|
| BDBM50173563 |
|---|
| n/a |
|---|
| Name | BDBM50173563 |
|---|
| Synonyms: | 1-{4-Fluoro-5-[(trityl-amino)-methyl]-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione | CHEMBL198660 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H26FN3O3 |
|---|
| Mol. Mass. | 471.5227 |
|---|
| SMILES | FC1CC(OC1CNC(c1ccccc1)(c1ccccc1)c1ccccc1)n1ccc(=O)[nH]c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
