| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamine synthetase |
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| Ligand | BDBM50174522 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_320773 (CHEMBL884728) |
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| Ki | 13000±n/a nM |
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| Citation |  Berlicki, L; Obojska, A; Forlani, G; Kafarski, P Design, synthesis, and activity of analogues of phosphinothricin as inhibitors of glutamine synthetase. J Med Chem48:6340-9 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamine synthetase |
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| Name: | Glutamine synthetase |
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| Synonyms: | GLN1B_ECOLI | glnA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51891.08 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_321474 |
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| Residue: | 469 |
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| Sequence: | MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKG
INESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRSTG
IADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWNSSTQYEGGNKGHRPAVKGGY
FPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYK
YVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLSKNGVNLFAGDKYAGLSEQALYYIG
GVIKHAKAINALANPTTNSYKRLVPGYEAPVMLAYSARNRSASIRIPVVSSPKARRIEVR
FPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDLPPEEAKEIPQVAGSLEEALN
ELDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV
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| BDBM50174522 |
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| n/a |
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| Name | BDBM50174522 |
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| Synonyms: | (S)-2-Amino-4-[(2-amino-ethyl)-hydroxy-phosphinoyl]-butyric acid; dihydrochloride | CHEMBL538331 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H15N2O4P |
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| Mol. Mass. | 210.1681 |
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| SMILES | N[C@@H](CCP(O)(O)CC=N)C(O)=O |
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| Structure | 
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