Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGlutamine synthetase
LigandBDBM50174527
Substrate/Competitorn/a
Meas. Tech.ChEMBL_320773
Ki 600±n/a nM
Citation Berlicki LObojska AForlani GKafarski P Design, synthesis, and activity of analogues of phosphinothricin as inhibitors of glutamine synthetase. J Med Chem 48:6340-9 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Glutamine synthetase
Name:Glutamine synthetase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:51891.08
Organism:Escherichia coli (strain K12)
Description:ChEMBL_321474
Residue:469
Sequence:
MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKG
INESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRSTG
IADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWNSSTQYEGGNKGHRPAVKGGY
FPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYK
YVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLSKNGVNLFAGDKYAGLSEQALYYIG
GVIKHAKAINALANPTTNSYKRLVPGYEAPVMLAYSARNRSASIRIPVVSSPKARRIEVR
FPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDLPPEEAKEIPQVAGSLEEALN
ELDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50174527
n/a
NameBDBM50174527
Synonyms:(S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric acid; hydrochloride | CHEMBL145114 | CHEMBL535153
TypeSmall organic molecule
Emp. Form.C5H12NO4P
Mol. Mass.181.1268
SMILESCP(O)(=O)CC[C@H](N)C(O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: