| Reaction Details |
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 | Report a problem with these data |
| Target | Guanine nucleotide-binding protein G(i) subunit alpha-3 |
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| Ligand | BDBM50174653 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_321105 (CHEMBL882871) |
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| EC50 | 12100±n/a nM |
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| Citation |  Manetti, D; Di Cesare Mannelli, L; Dei, S; Galeotti, N; Ghelardini, C; Romanelli, MN; Scapecchi, S; Teodori, E; Pacini, A; Bartolini, A; Gualtieri, F Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins. J Med Chem48:6491-503 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Guanine nucleotide-binding protein G(i) subunit alpha-3 |
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| Name: | Guanine nucleotide-binding protein G(i) subunit alpha-3 |
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| Synonyms: | GNAI3 | GNAI3_HUMAN | Guanine nucleotide-binding protein G(k), alpha-3 subunit |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40527.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_321105 |
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| Residue: | 354 |
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| Sequence: | MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG
YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT
PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVK
TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA
AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY
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| BDBM50174653 |
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| n/a |
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| Name | BDBM50174653 |
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| Synonyms: | 1-[4,4']Bipiperidinyl-1-yl-tridecan-1-one; hydrochloride | CHEMBL558775 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H44N2O |
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| Mol. Mass. | 364.6083 |
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| SMILES | CCCCCCCCCCCCC(=O)N1CCC(CC1)C1CCNCC1 |
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| Structure | 
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