| Reaction Details |
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 | Report a problem with these data |
| Target | Guanine nucleotide-binding protein G(o) subunit alpha |
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| Ligand | BDBM50174664 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_321106 (CHEMBL882872) |
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| EC50 | 23000±n/a nM |
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| Citation |  Manetti, D; Di Cesare Mannelli, L; Dei, S; Galeotti, N; Ghelardini, C; Romanelli, MN; Scapecchi, S; Teodori, E; Pacini, A; Bartolini, A; Gualtieri, F Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins. J Med Chem48:6491-503 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Guanine nucleotide-binding protein G(o) subunit alpha |
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| Name: | Guanine nucleotide-binding protein G(o) subunit alpha |
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| Synonyms: | GNAO1 | GNAO_HUMAN | Guanine nucleotide-binding protein G(o), alpha subunit 1 | guanine nucleotide-binding protein G(o) subunit alpha isoform a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40043.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_321106 |
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| Residue: | 354 |
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| Sequence: | MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG
FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF
SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV
KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET
TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA
AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY
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| BDBM50174664 |
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| n/a |
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| Name | BDBM50174664 |
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| Synonyms: | 1-Pentadecyl-piperidin-4-ylamine; dihydrochloride | CHEMBL535379 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H42N2 |
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| Mol. Mass. | 310.5609 |
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| SMILES | CCCCCCCCCCCCCCCN1CCC(N)CC1 |
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| Structure | 
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