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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Muscarinic acetylcholine receptor M1 | ||
| Ligand | BDBM50370682 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_320891 (CHEMBL872390) | ||
| Ki | 10±n/a nM | ||
| Citation |  Naito, R; Yonetoku, Y; Okamoto, Y; Toyoshima, A; Ikeda, K; Takeuchi, M Synthesis and antimuscarinic properties of quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives as novel muscarinic receptor antagonists. J Med Chem48:6597-606 (2005) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Muscarinic acetylcholine receptor M1 | |||
| Name: | Muscarinic acetylcholine receptor M1 | ||
| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 51390.46 | ||
| Organism: | RAT | ||
| Description: | P08482 | ||
| Residue: | 460 | ||
| Sequence: |
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| BDBM50370682 | |||
| n/a | |||
| Name | BDBM50370682 | ||
| Synonyms: | SOLIFENACIN | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H26N2O2 | ||
| Mol. Mass. | 362.4647 | ||
| SMILES | [H]C12CCN(CC1)C[C@@H]2OC(=O)N1CCc2ccccc2[C@@H]1c1ccccc1 |wD:8.10,21.25,TLB:9:8:2.3:6.5,(23.54,-9.18,;23.57,-7.64,;22.04,-8.3,;21.84,-6.92,;23.31,-6.28,;23.38,-4.63,;23.82,-5.74,;24.65,-6.88,;24.94,-8.28,;24.93,-9.81,;23.59,-10.56,;22.26,-9.79,;23.59,-12.1,;24.92,-12.9,;24.88,-14.45,;23.53,-15.19,;23.52,-16.72,;22.17,-17.47,;20.85,-16.68,;20.87,-15.14,;22.21,-14.39,;22.23,-12.84,;20.91,-12.06,;19.57,-12.81,;18.25,-12.02,;18.28,-10.47,;19.62,-9.73,;20.94,-10.52,)| | ||
| Structure | 
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