| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM50176060 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_321017 (CHEMBL883650) |
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| Ki | 518±n/a nM |
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| Citation |  Minetti, P; Tinti, MO; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Piersanti, G; Bartoccini, F; Tarzia, G 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization. J Med Chem48:6887-96 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM50176060 |
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| n/a |
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| Name | BDBM50176060 |
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| Synonyms: | 1-Methyl-2-[1,2,3]triazol-2-yl-1H-imidazo[4,5-c]pyridin-4-ylamine | CHEMBL198200 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H9N7 |
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| Mol. Mass. | 215.2147 |
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| SMILES | Cn1c(nc2c(N)nccc12)-n1nccn1 |
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| Structure | 
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