| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM21216 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_325562 (CHEMBL860281) |
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| Ki | 955±n/a nM |
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| Citation |  Novellino, E; Cosimelli, B; Ehlardo, M; Greco, G; Iadanza, M; Lavecchia, A; Rimoli, MG; Sala, A; Da Settimo, A; Primofiore, G; Da Settimo, F; Taliani, S; La Motta, C; Klotz, KN; Tuscano, D; Trincavelli, ML; Martini, C 2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching. J Med Chem48:8253-60 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM21216 |
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| n/a |
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| Name | BDBM21216 |
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| Synonyms: | 2-[4-(ethylsulfanyl)-1H-1,3-benzodiazol-2-yl]quinoxaline | 2-[4-(ethylsulfanyl)-1H-benzimidazol-2-yl]quinoxaline | CHEMBL198008 | benzimidazole-quinoxaline, C2 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N4S |
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| Mol. Mass. | 306.385 |
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| SMILES | CCSc1cccc2nc([nH]c12)-c1cnc2ccccc2n1 |
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| Structure | 
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